Remetinostat(SHP-141)是一种基于羟肟酸的组蛋白去乙酰化酶(HDAC)的抑制剂,目前正在开发应用于治疗皮肤T细胞淋巴瘤。
CAS:946150-57-8
分子式:C16H21NO6
分子量:323.34
纯度:98%
存储:Store at -20°C
Background:
Remetinostat (SHP-141) is a hydroxamic acid-based inhibitor of histone deacetylase enzymes (HDAC) which is under development for the treatment of cutaneous T-cell lymphoma[1].
[1]. Yijun Deng, et al. Process Development of the Soft Histone Deacetylate Enzyme Inhibitor SHP-141: Acylation of Methyl Paraben and Suberyl Hydroxamic Acid Formation. Org. Process Res. Dev. 2016, 20, 10, 1812-1820.