PF-06380101是Dolastatin10新型类似物,具有强细胞毒性,AMDE特性与其他auristatin类似物不同,ADCs中毒素分子。
CAS:1436391-86-4
分子式:C39H62N6O6S
分子量:743.01
纯度:98%
存储:Store at -20°C
Background:
PF-06380101 is a novel cytotoxic Dolastatin 10 analogue; with excellent potencies in tumor cell proliferation assays and differential ADME properties when compared to other synthetic auristatin analogues that are used in the preparation of ADCs.IC50 value: