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LLP-3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
LLP-3图片
CAS NO:1453835-43-2
规格:98%
分子量:535
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Survivin (also known as baculoviral IAP repeat-containing protein 5 (BIRC5)) is a member of the inhibitor of apoptosis (IAP) family that interacts with and inhibits the apoptotic function of several proteins.
CAS:1453835-43-2
分子式:C32H23ClN2O4
分子量:535
纯度:98%
存储:Store at -20°C

Background:

Survivin (also known as baculoviral IAP repeat-containing protein 5 (BIRC5)) is a member of the inhibitor of apoptosis (IAP) family that interacts with and inhibits the apoptotic function of several proteins. LLP-3 is a cell-permeable ligand of Survivin that blocks its interaction with Ran, resulting in the induction of apoptosis (IAP) in glioma stem cells (IC50 = 31 µM). It abolishes the growth of glioblastoma multiforme cell in spheres and in tumor slice cultures.