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Kynurenic Acid(hydrate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Kynurenic Acid(hydrate)图片
CAS NO:345909-35-5
规格:98%
分子量:189.2
包装与价格:
包装价格(元)
500mg电议
1g电议
5g电议

产品介绍
Kynurenic acid is a natural metabolite of tryptophan via the kynurenine pathway.
CAS:345909-35-5
分子式:C10H7NO3.XH2O
分子量:189.2
纯度:98%
存储:Store at -20°C

Background:

Kynurenic acid is a natural metabolite of tryptophan via the kynurenine pathway. It has pronounced effects on neuronal signaling and, thus, impacts diverse neurological systems. Kynurenic acid broadly antagonizes ionotopic glutamate receptors at high micromolar to millimolar concentrations and is used to pharmacologically block the activation of these receptors in vivo or in vitro. In addition, it reportedly has more potent effects at glutamate receptor subunit ζ-1 (Ki = 5.4 µM), GPR35 (EC50 = 39 µM), aryl hydrocarbon receptor (EC50 = 300 nM), and neuronal acetylcholine receptor α-7 (IC50 = 7 µM).