L-Iduronic acid is an epimer of glucuronic acid and a monosaccharide component of glycosaminoglycans (GAGs), including heparin and chondroitin sulfate B, found on the outer cell membrane.
CAS:61199-83-5
分子式:C6H9O7.Na
分子量:216.1
纯度:98%
存储:Store at -20°C
Background:
L-Iduronic acid is an epimer of glucuronic acid and a monosaccharide component of glycosaminoglycans (GAGs), including heparin and chondroitin sulfate B, found on the outer cell membrane. L-Iduronic acid is conformationally flexible, which allows it to bind metal ions and may be important for the antithrombotic activity of heparin. Iduronic acid-containing GAGs are selectively bound by basic fibroblast growth factor (bFGF), which prevents infection of Hep-2 cells with respiratory syncytial virus (RSV) in vitro.