Quinidine N-oxide is a pharmacologically inactive quinidine metabolite.
CAS:70116-00-6
分子式:C20H24N2O3
分子量:340.4
纯度:98%
存储:Store at -20°C
Background:
Quinidine N-oxide is a pharmacologically inactive quinidine metabolite. Quinidine, an antiarrhythmic agent, undergoes rapid first-pass metabolism by the cytochrome P450 isoforms CYP3A4, CYP2C9, and CYP2E1, with CYP3A4 being the most active enzyme in quinidine N-oxide formation.