Lidocaine is an anesthetic that blocks voltage-gated Na+ channels (IC50 = 128 μM) with selectivity over L-type Ca2+ channels and GABAA receptors.
CAS:50295-20-0
分子式:C13H20N2O.HCl
分子量:256.8
纯度:98%
存储:Store at -20°C
Background:
Lidocaine is an anesthetic that blocks voltage-gated Na+ channels (IC50 = 128 µM) with selectivity over L-type Ca2+ channels and GABAA receptors. Lidocaine can also have pronociceptive effects by activating the transient receptor potential (TRP) channel TRPA1. N-(2,6-Dimethylphenyl)-2-(ethylmethylamino)acetamide is a lidocaine impurity.