Amiodarone 是一种抗心律失常药,用于抑制 ATP 敏感性钾通道,IC50 为 19.1 μM。
CAS:1951-25-3
分子式:C25H29I2NO3
分子量:645.31
纯度:98%
存储:Store at -20°C
Background:
Amiodarone is an antiarrhythmic drug for inhibition of ATP-sensitive potassium channel with an IC50 of 19.1 μM.
[1]. Singh, B.N. and E.M. Vaughan Williams, The effect of amiodarone, a new anti-anginal drug, on cardiac muscle. Br J Pharmacol, 1970. 39(4): p. 657-67. [2]. Rosenbaum, M.B., et al., Clinical efficacy of amiodarone as an antiarrhythmic agent. Am J Cardiol, 1976. 38(7): p. 934-44.