CT7001hydrochloride是一种选择性的CDK7抑制剂，对CDK7/CycH/MAT1和CDK2/cycE1的IC50值分别为41nM和578nM。
CAS：1805789-54-1
分子式：C22H31ClN6O
分子量：430.97
纯度：98%
存储：Store at -20°C

Background:

CT7001 hydrochloride is a selective CDK7 inhibitor, with IC50s of 41 nM and 578 nM for CDK7/CycH/MAT1 and CDK2/cycE1, respectively.

CT7001 (ICEC0942) is a selective CDK7 inhibitor, with IC50s of 41 nM and 578 nM for CDK7/CycH/MAT1 and CDK2/cycE1, respectively[1].

[1]. Hazel P, et al. Inhibitor Selectivity for Cyclin-Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study. ChemMedChem. 2017 Mar 7;12(5):372-380.