15-OxoEDE is produced by the oxidation of 15-HEDE.
CAS:105835-44-7
分子式:C20H34O3
分子量:322.5
纯度:98%
存储:Store at -20°C
Background:
15-OxoEDE is produced by the oxidation of 15-HEDE. 15-OxoEDE inhibits 5-LO from RBL-1 cells with an IC50 of 55 µM, which is about 2-fold lower than 15(S)-HEDE. A related oxo-eicosanoid, 5-oxoETE, is biosynthesized from 5(S)-HETE by a specific dehydrogenase and has potent inflammatory activity.