Acetohydroxamicacid是一种有效的不可逆细菌和植物尿素酶抑制剂,用于辅助治疗慢性尿路感染。
CAS:546-88-3
分子式:C2H5NO2
分子量:75.07
纯度:98%
存储:Store at -20°C
Background:
Acetohydroxamic acid is a potent and irreversible inhibitor of bacterial and plant urease and also used as adjunctive therapy in chronic urinary infection.Target: UreaseAcetohydroxamic acid selectively inhibits arachidonate 5-lipoxygenase and thus has potential use in the treatment of asthma.
[1]. Sharma M, et al. Biotransformation of Acetamide to Acetohydroxamic Acid at Bench Scale Using Acyl Transferase Activity of Amidase of Geobacillus pallidus BTP-5x MTCC 9225. Indian J Microbiol. 2012 Mar;52(1):76-82.