Extracted?from?Fraxinus chinensis;Store?the?product?in?sealed,?cool?and?dry?condition.
CAS:6035-49-0
分子式:C12H12O5
分子量:236.22
纯度:98%
存储:Store at -20°C
Background:
Dimethylfraxetin is a Carbonic anhydrase inhibitor, with a Ki value of 0.0097 μM.
At CA I there is one stand out compound being Dimethylfraxetin (compound 17), a nanomolar CA I inhibitor. This trimethoxy coumarin is the most potent of any of the NP coumarins across the six CA isozymes of the present study[1].
参考文献:
[1]. Davis RA, et al. Natural product coumarins that inhibit human carbonic anhydrases. Bioorg Med Chem. 2013 Mar 15;21(6):1539-43.