CAS NO: | 102036-29-3 |
包装: | 20mg |
规格: | 98% |
市场价: | 3534元 |
分子量: | 304.09 |
Background:
Protosappanin B is a phenolic compound extracted from Lignum Sappan. Anti-cancer activity[1]. Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells[2].
Protosappanin B (12.5, 25, 50, 100, 200 μg/mL, 48 hours) dose-dependently inhibits tumor cells, with IC50s of 21.32 μg/mL, 26.73 μg/mL, and 76.53 μg/mL for SW-480, HCT-116, and BTT cells, respectively[1].
参考文献:
[1]. Yang X, et al. Antitumor Effects of Purified Protosappanin B Extracted From Lignum Sappan. Integr Cancer Ther. 2016 Mar;15(1):87-95.
[2]. Yang X, et al. Protosappanin B promotes apoptosis and causes G1 cell cycle arrest in human bladder cancer cells. Sci Rep. 2019 Jan 31;9(1):1048.