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Protosappanin B
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Protosappanin B图片
CAS NO:102036-29-3
包装:20mg
规格:98%
市场价:3534元
分子量:304.09

产品介绍
Extracted?from?Caesalpinia sappan L.;Store?the?product?in?sealed,?cool?and?dry?condition
CAS:102036-29-3
分子式:C16H16O6
分子量:304.09
纯度:98%
存储:Store at -20°C

Background:

Protosappanin B is a phenolic compound extracted from Lignum Sappan. Anti-cancer activity[1]. Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells[2].


Protosappanin B (12.5, 25, 50, 100, 200 μg/mL, 48 hours) dose-dependently inhibits tumor cells, with IC50s of 21.32 μg/mL, 26.73 μg/mL, and 76.53 μg/mL for SW-480, HCT-116, and BTT cells, respectively[1].


参考文献:
[1]. Yang X, et al. Antitumor Effects of Purified Protosappanin B Extracted From Lignum Sappan. Integr Cancer Ther. 2016 Mar;15(1):87-95.
[2]. Yang X, et al. Protosappanin B promotes apoptosis and causes G1 cell cycle arrest in human bladder cancer cells. Sci Rep. 2019 Jan 31;9(1):1048.