N-CBZ-Phe-Arg-AMC (Z-FR-AMC) 是一种组织蛋白酶底物，可用于评估溶酶体组织蛋白酶的活性。
CAS：65147-22-0
分子式：C33H36N6O6
分子量：612.68
纯度：98%
存储：Store at -20°C

Background:

N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes[1][2].

[1]. Xu P, et al. Ascorbic acid modulation of iron homeostasis and lysosomal function in trabecular meshwork cells. J Ocul Pharmacol Ther. 2014 Mar-Apr;30(2-3):246-53. [2]. Porter K,et al. Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis. Autophagy. 2013 Apr;9(4):581-94.