MF498 is a selective E prostanoid receptor 4 antagonist. It relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis. References: Tse KH, Chow KB, Wise H. PGE2 released by primary sensory neurons modulates Toll-like receptor 4 activities through an EP4 receptor-dependent process. J Neuroimmunol. 2016 Apr 15;293:8-16. doi: 10.1016/j.jneuroim.2016.02.005. PubMed PMID: 27049555.
纯度:≥98%
CAS:915191-42-3