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Silydianin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Silydianin图片
CAS NO:29782-68-1
包装:20mg
规格:98%
市场价:1746元
分子量:482.44

产品介绍
Extracted?from?whole herb and Achene of Silybum marianum L.Gaertn.;Store?the?product?in?sealed,?cool?and?dry?condition
CAS:29782-68-1
分子式:C25H22O10
分子量:482.44
纯度:98%
存储:Store at -20°C

Background:

Silydianin is an active constituent of Silybium marianum, with exhibit anti-collagenase, antitumor and anti-elastase activities. Silydianin is a natural protein tyrosine phosphatase 1B (PTP1B) with an IC50 of 17.38?μM. Silydianin has inhibitory effect on the in vitro production and release of oxidative products[1][2][3].


参考文献:
[1]. Vostálová J, et al. Skin Protective Activity of Silymarin and its Flavonolignans. Molecules. 2019 Mar 14;24(6).
[2]. Qin N, et al. Identification of flavonolignans from Silybum marianum seeds as allosteric protein tyrosine phosphatase 1B inhibitors. J Enzyme Inhib Med Chem. 2018 Dec;33(1):1283-1291.
[3]. Zielińska-Przyjemska M, et al. An in vitro study of the protective effect of the flavonoid silydianin against reactive oxygen species. Phytother Res. 2006 Feb;20(2):115-9.