PROTACLinker2是用于将酪氨酸激酶(TKI)抑制剂连接到E3招募配体上的一种PROTAC连接体。
CAS:1835705-52-6
分子式:C21H41ClO4
分子量:393
纯度:98%
存储:Store at -20°C
Background:
PROTAC Linker 2 is a PROTAC linker utilized to connect the respective tyrosine kinase inhibitor (TKI) to the E3 recruiting ligand.
[1]. Lai AC, et al. Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL. Angew Chem Int Ed Engl. 2016 Jan 11;55(2):807-10. [2]. ARYL SULFONOHYDRAZIDES. US 20170121321 A1.