Sclerotiorin is a natural product isolated primarily from Penicillium species.
CAS:549-23-5
分子式:C21H23ClO5
分子量:390.9
纯度:98%
存储:Store at -20°C
Background:
Sclerotiorin is a natural product isolated primarily from Penicillium species. It inhibits soybean lipoxygenase-1 with an IC50 value of 4.2 µM. Sclerotiorin also exhibits a number of other activities including inhibition of cholesterol ester transfer protein (IC50 = 19.4 µM),, inhibition of Grb2-Shc interaction (IC50 = 22 µM),, and antagonism of endothelin receptors (IC50 = 114 and 152 µM for human ETA and ETB, respectively).