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Ophiopogonin D'
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ophiopogonin D'图片
CAS NO:65604-80-0
包装:10mg
规格:98%
市场价:2691元
分子量:855.02

产品介绍
Extracted?from?Ophiopogon japonicus (Thunb.) Ker-Gawl. dried tuberous roots;Store?the?product?in?sealed,?cool?and?dry?condition
CAS:65604-80-0
分子式:C44H70O16
分子量:855.02
纯度:98%
存储:Store at -20°C

Background:

Ophiopogonin D', isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D' shows cytotoxic activity against two human tumor cell lines MG-63 and SNU387 with IC50s of 3.09 μM and 3.63 μM, respectively[1]. Ophiopogonin D' activates SIRT1 in a dose-dependent manner[2].


参考文献:
[1]. Wang L , et al. Homo-aro-cholestane, furostane and spirostane saponins from the tubers of Ophiopogonjaponicus. Phytochemistry. 2017 Apr;136:125-132.
[2]. Wang Y, et al. Specific Turn-On Fluorescent Probe with Aggregation-Induced EmissionCharacteristics for SIRT1 Modulator Screening and Living-Cell Imaging. Anal Chem. 2015;87(10):5046-9.