Sotetsuflavone是一个强的DENV-NS5RdRp抑制剂,IC50值是0.16uM.
CAS:2608-21-1
分子式:C31H20O10
分子量:552.48
纯度:98%
存储:Store at -20°C
Background:
Sotetsuflavone is a potent inhibitor of DENV-NS5 RdRp (Dengue virus NS5 RNA-dependent RNA polymerase) with an IC50 of 0.16 uM, is the most active compound of this series .
[1]. Coulerie P et al. Structure-activity relationship study of biflavonoids on the Dengue virus polymerase DENV-NS5 RdRp. Planta Med. 2013 Sep;79(14):1313-8. [2]. Li SH et al. Chemical constituents from Amentotaxus yunnanensis and Torreyayunnanensis. J Nat Prod. 2003 Jul;66(7):1002-5.