E3LigaseLigand-LinkerConjugates21是一种合成化合物,包含E3泛素连接酶配体与PROTAC连接物,可以将靶蛋白与泛素化机制结合起来。
CAS:1957236-20-2
分子式:C23H30N4O9
分子量:506.51
纯度:98%
存储:Store at -20°C
Background:
E3 Ligase Ligand-Linker Conjugates 21 is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology.
E3 Ligase Ligand-Linker Conjugates 21 is composed of Degron (E3 ubiquitin ligase) and a linker, and they are used in PROTAC technology. E3 Ligase Ligand-Linker Conjugates 21 binds to the targeting ligand to induce the target protein (including BRD4, BRD2, and BRD3) degradation[1].
[1]. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017007612 A1