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α-Spinasterol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
α-Spinasterol图片
CAS NO:481-18-5
包装:1mg
规格:98%
市场价:1011元
分子量:412.69

产品介绍
TRPV1 antagonist
CAS:481-18-5
分子式:C29H48O
分子量:412.69
纯度:98%
存储:Store at -20°C

Background:

α-Spinasterol, isolated from Spinacia oleracea, has antibacterial activity[1]. α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 values of 16.17 μM and 7.76 μM, respectively[2].


参考文献:
[1]. Brusco I, et al. α-Spinasterol: a COX inhibitor and a transient receptor potential vanilloid 1 antagonist presents an antinociceptive effect in clinically relevant models of pain in mice. Br J Pharmacol. 2017 Dec;174(23):4247-4262.
[2]. Yang X, et al. A novel method for synthesis of α-spinasterol and its antibacterial activities in combination with ceftiofur. Fitoterapia. 2017 Jun;119:12-19.