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3,4,5-Tricaffeoylquinic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
3,4,5-Tricaffeoylquinic acid图片
CAS NO:86632-03-3
包装:5mg
规格:98%
市场价:3227元
分子量:678.59

产品介绍
Extracted?from?C odonop sis nervosa ( Chipp) N annf;Store?the?product?in?sealed,?cool?and?dry?condition
CAS:86632-03-3
分子式:C34H30O15
分子量:678.59
纯度:98%
存储:Store at -20°C

Background:

3,4,5-Tricaffeoylquinic acid is isolated from barks of Ilex rotunda Thunb, used in the research of the pro-inflammatory mediator-induced skin disease[1].


3,4,5-Tricaffeoylquinic acid (0-50 μM) reduces TNF-α-induced production of cytokines in HEK001 keratinocytes[1]. 3,4,5-Tricaffeoylquinic acid (15 μM, 35 min) inhibits TNF-α-induced IkBα phosphorylation and activation of NF-κB[1].


参考文献:
[1]. Lee CS, et al. 3,4,5-Tricaffeoylquinic acid inhibits tumor necrosis factor-α-stimulated production of inflammatory mediators in keratinocytes via suppression of Akt- and NF-κB-pathways. Int Immunopharmacol. 2011 Nov;11(11):1715-23.