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Abietic Acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Abietic Acid图片
CAS NO:514-10-3
规格:98%
分子量:302.5
包装与价格:
包装价格(元)
10g电议
25g电议
50g电议
100g电议

产品介绍
Abietic acid is an abietane diterpene originally isolated from wood resin that has diverse biological activities, including enzyme inhibitory, antiproliferative, antibacterial, and anti-obesity properties.
CAS:514-10-3
分子式:C20H30O2
分子量:302.5
纯度:98%
存储:Store at -20°C

Background:

Abietic acid is an abietane diterpene originally isolated from wood resin that has diverse biological activities, including enzyme inhibitory, antiproliferative, antibacterial, and anti-obesity properties. It inhibits soybean 5-lipoxygenase (5-LO) and rat prostate testosterone 5α-reductase in cell-free assays (IC50s = 29.5 and 56 μM, respectively). Abietic acid selectively inhibits proliferation of HeLa cervical cancer cells over noncancerous Vero cells (IC50s = 15 and 53 μM, respectively) and inhibits the growth of S. epidermidis, P. acnes, and S. mitis bacteria (MICs = 8, 4, and 16 μg/ml, respectively). It induces expression of fatty acid binding protein 2 and lipoprotein lipase (LPL) in differentiated 3T3-L1 mouse adipocytes when used at a concentration of 25 μM. Abietic acid (40 mg/kg per day) also decreases body and adipose tissue weight in mice fed a high-fat diet.