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DEA NONOate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
DEA NONOate图片
CAS NO:372965-00-9
规格:98%
分子量:206.3
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议
500mg电议

产品介绍
DEA NONOate is a NO donor.
CAS:372965-00-9
分子式:C4H11N3O2.C4H11N
分子量:206.3
纯度:98%
存储:Store at -20°C

Background:

DEA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 2 minutes and 16 minutes at 37°C and 22-25°C, pH 7.4, respectively, to liberate 1.5 moles of NO per mole of parent compound.[1][2]


Reference:
[1]. Maragos, C.M., Morley, D., Wink, D.A., et al. Complexes of ?NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects. Journal of Medicinal Chemistry 34, 3242-3247 (1991).
[2]. Keefer, L.K., Nims, R.W., Davies, K.M., et al. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms. Methods in Enzymology 268, 281-293 (1996).