BIPM novel and highly potent Rho-associated protein kinase 2 (ROCK2) inhibitor. Exposure of SH-SY5Y cells to BIPM led to significant changes in neurite length, cell migration and actin stress fibers. Further experiments demonstrated that BIPM was able to significantly inhibit phosphorylation of cofilin, a regulatory protein of actin cytoskeleton. References: Chong CM, Kou MT, Pan P, Zhou H, Ai N, Li C, Zhong HJ, Leung CH, Hou T, Lee SM. Discovery of a novel ROCK2 inhibitor with anti-migration effects via docking and high-content drug screening. Mol Biosyst. 2016 Aug 16;12(9):2713-21. doi: 10.1039/c6mb00343e. PubMed PMID: 27354305.

纯度：≥98%

CAS：1070424-33-7