Methyltetrazine-PEG5-alkyne is a PEG analogue containing an alkyne group and a hydrophilic PEG spacer. This reagent enables simple and efficient incorporation of a tetrazine moiety onto antibodies, cysteine-containing peptides, and other thiol-containing molecules. The alkynes can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. References: Sano K, Nakajima T, Miyazaki K, Ohuchi Y, Ikegami T, Choyke PL, Kobayashi H. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. Bioconjug Chem. 2013 May 15;24(5):811-6. doi: 10.1021/bc400050k. Epub 2013 May 3. PubMed PMID: 23600922; PubMed Central PMCID: PMC3674550.

纯度：≥98%

CAS：1802907-97-6