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3'-sulfo Galactosylsphingosine(ammonium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
3'-sulfo Galactosylsphingosine(ammonium salt)图片
CAS NO:1246681-32-2
包装:1mg
规格:98%
市场价:8241元
分子量:558.7

产品介绍
3'-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group.
CAS:1246681-32-2
分子式:C24H46NO10S.NH4
分子量:558.7
纯度:98%
存储:Store at -20°C

Background:

3’-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group. It decreases migration and adhesion of B35 neuroblastoma cells and increases cell rounding when used at a concentration of 20 µM. It also inhibits PKC and cytochrome c oxidase activity when used at concentrations of 150 and 50-100 µM, respectively. 3’-sulfo Galactosylsphingosine accumulates in patients with metachromatic leukodystrophy, a lysosomal storage disorder characterized by arylsulfatase A (ASA) deficiency leading to progressive demyelination and neuromotor deficits. In mice lacking ASA, levels of 3’-sulfo galactosylsphingosine increase after one month of age followed by demyelination and neuromotor deficits. 3’-sulfo Galactosylsphingosine has been used as a standard for the quantification of 3’-sulfo galactosylsphingosine by LC-MS.