CAS NO: | 864953-39-9 |
规格: | 98% |
分子量: | 704.62 |
包装 | 价格(元) |
2mg | 电议 |
5mg | 电议 |
Background:
Fostemsavir Tris (BMS-663068 (Tris)) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir Tris (BMS-663068 (Tris)) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells. HIV-1[1]
Fostemsavir Tris has good antiviral activity in subjects infected with virus shown to be susceptible (IC50,<100 nM) to the agent[1].
[1]. Nowicka-Sans B, et al. In vitro antiviral characteristics of HIV-1 attachment inhibitor BMS-626529, the active component of the prodrug BMS-663068. Antimicrob Agents Chemother. 2012 Jul;56(7):3498-507.