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Fostemsavir Tris
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fostemsavir Tris图片
CAS NO:864953-39-9
规格:98%
分子量:704.62
包装与价格:
包装价格(元)
2mg电议
5mg电议

产品介绍
Fostemsavir Tris (BMS-663068 (Tris)) 是HIV-1附着抑制剂。
CAS:864953-39-9
分子式:C29H37N8O11P
分子量:704.62
纯度:98%
存储:Store at -20°C

Background:

Fostemsavir Tris (BMS-663068 (Tris)) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir Tris (BMS-663068 (Tris)) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells. HIV-1[1]



Fostemsavir Tris has good antiviral activity in subjects infected with virus shown to be susceptible (IC50,<100 nM) to the agent[1].


[1]. Nowicka-Sans B, et al. In vitro antiviral characteristics of HIV-1 attachment inhibitor BMS-626529, the active component of the prodrug BMS-663068. Antimicrob Agents Chemother. 2012 Jul;56(7):3498-507.