CAS NO: | 82909-47-5 |
规格: | 98% |
分子量: | 224.3 |
包装 | 价格(元) |
5mg | 电议 |
100ug | 电议 |
500ug | 电议 |
1mg | 电议 |
Background:
Myristic acid is a 14-carbon saturated (14:0) fatty acid. In vivo, it is commonly added covalently to the N-terminus of proteins in a co-translational process termed N-myristoylation. The sirtuin SIRT6 removes this acyl group from myristoylated TNF-α, enhancing secretion. Myristic acid alkyne is a form of this myristic acid with an ω-terminal alkyne. Such terminal alkyne groups can be used in linking reactions, known as click chemistry, characterized by high dependability and specificity of azide-alkyne bioconjugation reactions. Click chemistry has only recently been applied to the study of lipids.