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Dabigatran Acyl-β-D-Glucuronide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dabigatran Acyl-β-D-Glucuronide图片
CAS NO:1015167-40-4
包装:1mg
规格:98%
市场价:9828元
分子量:647.6

产品介绍
Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran.
CAS:1015167-40-4
分子式:C31H33N7O9
分子量:647.6
纯度:98%
存储:Store at -20°C

Background:

Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran . The prodrug of dabigatran, dabigatran etexilate , is hydrolyzed by plasma esterases to form dabigatran, which is metabolized primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT2B15 to form dabigatran acyl-β-D-glucuronide. Dabigatran acyl-β-D-glucuronide increases activated partial thromboplastin time (aPTT) in isolated human platelet-poor plasma equipotently to dabigatran.