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[Sar9,Met(O2)11]-Substance P
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
[Sar9,Met(O2)11]-Substance P图片
CAS NO:110880-55-2
包装:1mg
规格:98%
市场价:1376元
分子量:1393

产品介绍
NK1 tachykinin receptor agonist
CAS:110880-55-2
分子式:C64H100N18O15S
分子量:1393
纯度:98%
存储:Store at -20°C

Background:

[Sar9,Met(O2)11]-Substance P is a tachykinin NK1 receptor selective agonist.
[Sar9,Met(O2)11]-Substance P and septide (10-100?pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P is the sole to produce grooming[1].
Reference:
[1]. Cellier E, et al. Characterization of central and peripheral effects of septide with the use of five tachykinin NK1 receptor antagonists in the rat. Br J Pharmacol. 1999 Jun;127(3):717-28.