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Byakangelicin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Byakangelicin图片
CAS NO:19573-01-4
包装:20mg
规格:98%
市场价:4056元
分子量:334.11

产品介绍
Extracted?from?Ruta graveolens L. roots;Store?the?product?in?sealed,?cool?and?dry?condition
CAS:19573-01-4
分子式:C17H18O7
分子量:334.11
纯度:98%
存储:Store at -20°C

Background:

Byakangelicin, one of the active compounds found in the roots of Angelica gigas, can serve as a modulator to improve brain accumulation of diverse active compounds (Umb, Cur, and Dox) and enhance therapeutic effects[1]. Byakangelicin is likely to increase the expression of all PXR target genes (such as MDR1) and induce a wide range of drug-drug interactions. Byakangelicin can inhibit the effects of sex hormones, it may increase the catabolism of endogenous hormones[2].


参考文献:
[1]. Kang YY, et al. Byakangelicin as a modulator for improved distribution and bioactivity of natural compounds and synthetic drugs in the brain. Phytomedicine. 2019 May 17;62:152963.
[2]. Yang J, et al. Byakangelicin induces cytochrome P450 3A4 expression via transactivation of pregnane X receptors in human hepatocytes. Br J Pharmacol. 2011 Jan;162(2):441-51.