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AVX 13616
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AVX 13616图片
CAS NO:900814-48-4
规格:98%
分子量:955.06
包装与价格:
包装价格(元)
2mg电议
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
AVX 13616具有体内抗菌性,尤其对耐药的葡萄球菌病原体有效。
CAS:900814-48-4
分子式:C50H73Cl2N7O7
分子量:955.06
纯度:98%
存储:Store at -20°C

Background:

AVX 13616 shows the potent in vivo antibacterial activity of Avexa’s lead antibacterial candidate; particularly against drug-resistant Staphylococcus pathogens.IC50 value: 2-4 ug/ml (MICs)Target: antibacterial agent AVX13616 was as active as mupirocin in a nasal decolonization model but required only a single application. The compounds are being developed for topical indications and/or wound infection/catheter-related infections. AVX13616 and other compounds showed broad spectrum antibacterial activity against a range of isolates with MICs of 2-4 micrograms per millilitre against S. aureus, coagulase negative staphylococci, enterococci, MRSA, VISA and VRSA. A single application of 5% (w/w) AVX13616 (approximately equimolar to 2% mupirocin) was as effective as 2% mupirocin administered twice a day for five days in nasal decolonisation of MRSA in mice.




[1]. Avexa Presents Data from Apricitabine and Antibacterial Programs at two International Conferences