Tyrosinase 369-377, human 是一种来自酪氨酸酶 (tyrosinase) 的 HLA-A2.1 限制性表位多肽,已被应用于开发具有混合疗效的肿瘤靶向疫苗。
CAS:168650-46-2
分子式:C42H66N10O16S2
分子量:1031.16
纯度:98%
存储:Store at -20°C
Background:
Tyrosinase 369-377, human is a HLA-A2.1-restricted epitope derived from tyrosinase, has been used to develop tumor-targeted vaccines with mixed efficacy[1][2].
[1]. Guillaume B, et al. Analysis of the processing of seven human tumor antigens by intermediate proteasomes. J Immunol. 2012 Oct 1;189(7):3538-47.
[2]. Mitchell MS, et al. Phase I trial of adoptive immunotherapy with cytolytic T lymphocytes immunized against a tyrosinase epitope. J Clin Oncol. 2002 Feb 15;20(4):1075-86.