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4-hydroxy Nonenal Alkyne
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
4-hydroxy Nonenal Alkyne图片
CAS NO:1011268-23-7
规格:98%
分子量:152.2
包装与价格:
包装价格(元)
5mg电议
100ug电议
500ug电议
1mg电议

产品介绍
4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid.
CAS:1011268-23-7
分子式:C9H12O2
分子量:152.2
纯度:98%
存储:Store at -20°C

Background:

4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid. It is considered a potential causal agent in numerous diseases, including chronic inflammation, neurodegenerative diseases, atherosclerosis, diabetes, and cancer, in part because it covalently modifies DNA and proteins resulting in genetic mutations and altered cell signaling, respectively. 4-HNE Alkyne is a form of 4-HNE with a terminal alkyne. Such terminal alkyne groups can be used in linking reactions, known as click chemistry, characterized by high dependability and specificity of azide-alkyne bioconjugation reactions. Click chemistry has only recently been applied to the study of oxidized lipids.