1,2-Diheptanoyl-sn-glycero-3-PC (DHPC-C7) is a synthetic phosphatidylcholine containing the short-chain (7:0) heptanoic acid at the sn-1 and sn-2 positions.
CAS：39036-04-9
分子式：C22H44NO8P
分子量：481.6
纯度：98%
存储：Store at -20°C

Background:

1,2-Diheptanoyl-sn-glycero-3-PC (DHPC-C7) is a synthetic phosphatidylcholine containing the short-chain (7:0) heptanoic acid at the sn-1 and sn-2 positions. It is commonly used in the formation of lipid bilayers and mixed micelles that has a critical micelle concentration (CMC) of 1.6 mM. Short-chain phospholipids, such as DHPC-C7 and 1,2-dihexanoyl-sn-glycero-PC , increase the formation rate of substrate-supported planar phospholipid bilayers on glass and silica. DHPC-C7 inhibits insulin fibril formation in vitro in a concentration-dependent manner and inhibits cytotoxicity induced by insulin fibril formation in PC12 and SH-SY5Y cells when used at concentrations ranging from 0.5 to 4 mM.