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Tetrahydropiperine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tetrahydropiperine图片
CAS NO:23434-88-0
规格:98%
分子量:289.4
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Tetrahydropiperine is a derivative of piperine and an arylpentanamide originally isolated from P.
CAS:23434-88-0
分子式:C17H23NO3
分子量:289.4
纯度:98%
存储:Store at -20°C

Background:

Tetrahydropiperine is a derivative of piperine and an arylpentanamide originally isolated from P. longum that has diverse biological activities. It is an agonist of transient receptor potential vanilloid type 1 (TRPV1; EC50 = 6.3 µM). It inhibits the cytochrome P450 (CYP) isoform CYP1A1/arylhydrocarbon hydroxylase (AHH; IC50 = 23 µM) and 7-methoxycoumarin O-demethylase (MOCD) activity (IC50 = 25 µM) in rat liver microsomes. Tetrahydropiperine increases skin pigmentation in a mouse model of vitiligo when 100 µl of a 175 mM solution is administered topically, an effect that can be enhanced by subsequent suberythemal ultraviolet radiation (UVR). Formulations containing tetrahydropiperine have been used to increase bioavailability of compounds applied to the skin.