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Lometrexol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Lometrexol图片
CAS NO:106400-81-1
规格:98%
分子量:443.5
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Glycinamide ribonucleotide formyltransferase (GART) is a folate-dependent enzyme required for de novo purine synthesis.
CAS:106400-81-1
分子式:C21H25N5O6
分子量:443.5
纯度:98%
存储:Store at -20°C

Background:

Glycinamide ribonucleotide formyltransferase (GART) is a folate-dependent enzyme required for de novo purine synthesis. Lometrexol is a folate analog antimetabolite with antineoplastic activity. At nanomolar conentrations, it inhibits GART preventing de novo purine synthesis, inhibiting DNA synthesis, arresting cells in the S phase of the cell cycle, and inhibiting tumor cell proliferation.