Digitoxigenin is a cardenolide and aglycone constituent of digitoxin, an extract from the foxglove plant, D.
CAS:143-62-4
分子式:C23H34O4
分子量:374.5
纯度:98%
存储:Store at -20°C
Background:
Digitoxigenin is a cardenolide and aglycone constituent of digitoxin, an extract from the foxglove plant, D. purpurea. It elicits cardiac contraction and cardiotonic effects by inhibiting the Na+/K+ ATPase via binding at the digitalis receptor site with nanomolar potency. Digitoxigenin is highly cytotoxic, inhibiting Na+/K+ ATPase-dependent protein synthesis, and has been examined for use as an antitumor compound.