Alclometasone dipropionate (ACM) is a corticosteroid.
CAS:66734-13-2
分子式:C28H37ClO7
分子量:521
纯度:98%
存储:Store at -20°C
Background:
Alclometasone dipropionate (ACM) is a corticosteroid. It reduces cutaneous anaphylaxis reactions induced by tuberculin or albumin in mice when administered topically (20 μl of a 0.1% solution). ACM also inhibits androgen-dependent cytochrome P450 activity and the O-depropylation activity of 7-alkoxy-coumarin O-dealkylase in a dose-dependent manner in male rats but has no effect on hepatic drug metabolism in female rats or mice of both sexes. Formulations containing ACM have been used to treat radiation and allergic contact dermatitis.