PSB-12379是一种有效的Ecto-5'-Nucleotidase(CD73)抑制剂,Kis值为9.03nM(鼠)和2.21nM(人)。
CAS:1802226-78-3
分子式:C18H23N5O9P2
分子量:515.35
纯度:98%
存储:Store at -20°C
Background:
PSB-12379 is a potent Ecto-5’-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human).
[1]. Bhattarai S, et al. α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5’-Nucleotidase (CD73) Inhibitors. J Med Chem. 2015 Aug 13;58(15):6248-63.