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15(R)-Prostaglandin D2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
15(R)-Prostaglandin D2图片
CAS NO:59894-05-2
规格:98%
分子量:352.5
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Many of the effects of prostaglandin D2 (PGD2) are transduced via a traditional 7-transmembrane GPCR, the DP1 receptor.
CAS:59894-05-2
分子式:C20H32O5
分子量:352.5
纯度:98%
存储:Store at -20°C

Background:

Many of the effects of prostaglandin D2 (PGD2) are transduced via a traditional 7-transmembrane GPCR, the DP1 receptor. However, in certain leukocytes and other immune cells, a second PGD2 receptor referred to as the CRTH2 or DP2 receptor has been cloned and characterized. 15(R)-15-methyl PGD2 is a surprisingly potent agonist at the DP2 receptor, being about 5 times more potent than PGD2 itself. 15(R)-PGD2 has the potential to be produced endogenously as a natural ligand for DP2, unlike the synthetic 15-methyl analogs. In preliminary reports, 15(R)-PGD2 has also been reported to be a potent and selective DP2 receptor agonist.