6-trans LTB4 is produced by the non-enzymatic hydrolysis of LTA4.
CAS:71652-82-9
分子式:C20H32O4
分子量:336.5
纯度:98%
存储:Store at -20°C
Background:
6-trans LTB4 is produced by the non-enzymatic hydrolysis of LTA4. Oxidative decomposition of cysteinyl-leukotrienes such as LTC4 in the presence of myeloperoxidase and hypochlorous acid can also produce 6-trans LTB4, but the physiologic importance of this mechanism is not clear. 6-trans LTB4 is relatively inactive compared to LTB4, but chemoattractant properties in neutrophils have been reported.