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Chrysomycin B
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Chrysomycin B图片
CAS NO:83852-56-6
规格:98%
分子量:496.5
包装与价格:
包装价格(元)
250ug电议
1mg电议

产品介绍
Chrysomycin B is an antibiotic isolated from a strain of Streptomyces.
CAS:83852-56-6
分子式:C27H28O9
分子量:496.5
纯度:98%
存储:Store at -20°C

Background:

Chrysomycin B is an antibiotic isolated from a strain of Streptomyces. It differs from its analog chrysomycin A by having a methyl, rather than vinyl, group in the 8-position of the chromophore. Like its analog, chrysomycin B suppresses the growth of transplantable tumors in mice, an effect that may be related to its ability to bind DNA. It also causes DNA damage in the human lung adenocarcinoma A549 cell line and inhibits topoisomerase II. Chrysomycin B is structurally very similar to gilvocarcin V, which promotes DNA cross-linking with histone 3 and GRP78 when photoactivated by near-UV light.