platelet-activating factor (PAF) receptor antagonist
CAS:105219-56-5
分子式:C22H22N5O2SCl
分子量:455.96
纯度:98%
存储:Store at -20°C
Background:
Apafant (WEB 2086), a potent platelet-activating factor (PAF) antagonist, inhibits PAF binding to human PAF receptors with a Ki of 9.9 nM[1].
参考文献:
[1]. Kato M, et al. Apafant, a potent platelet-activating factor antagonist, blocks eosinophil activation and is effective in the chronic phase of experimental allergic conjunctivitis in guinea pigs. J Pharmacol Sci. 2004 Aug;95(4):435-42.