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Praziquantel
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Praziquantel图片
CAS NO:55268-74-1
规格:98%
分子量:312.41
包装与价格:
包装价格(元)
50mg电议
5g电议

产品介绍
anthelmintic
CAS:55268-74-1
分子式:C19H24N2O2
分子量:312.41
纯度:98%
存储:Store at -20°C

Background:

Praziquantel is an anthelmintic effective against flatworms.Target: AntiparasiticPraziquantel is the drug of choice for treatment of all human schistosomes. Infected mice were treated with increasing Praziquantel doses until the highest dose of 3 × 300 mg/Kg was reached. The effect of Praziquantel treatment on the parasite population was assessed using five polymorphic microsatellite markers. Parasitological and genetic data were compared with those of the untreated control. After six parasite generations submitted to treatment, it was possible to obtain a S. mansoni population with decreased susceptibility to Praziquantel. In our experiments we also observed that female worms were more susceptible to Praziquantel than male worms [1, 2].


参考文献:
[1]. Coeli, R., et al., Praziquantel treatment decreases Schistosoma mansoni genetic diversity in experimental infections. PLoS Negl Trop Dis, 2013. 7(12): p. e2596.
[2]. Mekonnen, A., et al., Efficacy of Praziquantel against Schistosoma haematobium in Dulshatalo village, western Ethiopia. BMC Res Notes, 2013. 6: p. 392.