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Eldecalcitol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Eldecalcitol图片
CAS NO:104121-92-8
规格:98%
分子量:490.72
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍

Eldecalcitol (ED-71) 是1,25-二羟基维生素D3的类似物。
CAS:104121-92-8
分子式:C30H50O5
分子量:490.72
纯度:98%
存储:Store at -20°C

Background:

Eldecalcitol (ED-71) is an analog of 1,25-dihydroxyvitamin D3 that improves bone mineral density. IC50 value:Target: Vd analogEldecalcitol (ED-71) is more efficacious than alfacalcidol in preventing vertebral and wrist fractures in osteoporotic patients with vitamin D sufficiency, with a safety profile similar to alfacalcidol.

[1]. Matsumoto T.Osteoporosis Treatment by a New Active Vitamin D3 Compound, Eldecalcitol, in Japan.Curr Osteoporos Rep. 2012 Aug 24. [2]. Shiraki M, et al. Eldecalcitol normalizes bone turnover markers regardless of their pre-treatment levels.Curr Med Res Opin. 2012 Aug 23. [3]. Matsumoto T, Endo I.Eldecalcitol for the treatment of osteoporosis.Drugs Today (Barc). 2012 Mar;48(3):189-96. [4]. Sakai S, et al.Combination therapy with eldecalcitol and alendronate has therapeutic advantages over monotherapy by improving bone strength.Bone. 2012 May;50(5):1054-63. Epub 2012 Feb 17. [5]. Sanford M, McCormack PL.Spotlight on eldecalcitol in osteoporosis.Drugs Aging. 2012 Jan 1;29(1):69-71.