Background:

Mycro 3 is potent and selective for c-Myc in whole cell assays.

Mycro 3 is potent and selective for c-Myc in whole cell assays, with weak inhibitory activity against Activator protein 1 (AP-1), Mycro 3 has a superior specificity profile to its predecessors. Mycro 3 inhibits the interaction between c-Myc and Max. Mycro 3 has high selectivity and inhibits c-Myc/Max dimerization and conjugation with DNA[1].

[1]. Chen BJ, et al. Small molecules targeting c-Myc oncogene: promising anti-cancer therapeutics. Int J Biol Sci. 2014 Sep 13;10(10):1084-96.