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Galactosylsphingosine(d18:1)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Galactosylsphingosine(d18:1)图片
CAS NO:2238-90-6
规格:98%
分子量:461.6
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Galactosylsphingosine is a galactoside of sphingosine and a constituent of cerebrosides.
CAS:2238-90-6
分子式:C24H47NO7
分子量:461.6
纯度:98%
存储:Store at -20°C

Background:

Galactosylsphingosine is a galactoside of sphingosine and a constituent of cerebrosides. The lysosomal enzyme β-galactosylceramidase is responsible for cleaving the glycosydic linkage of galactosylceramide and galactosylsphingosine. Accumulation of galactosylsphingosine during β-galactosylceramidase deficiency, as seen with Krabbe disease, is cytotoxic and preferentially affects oligodendrocytes, leading to progressive demyelination and infiltration of activated macrophages into the brain.